Signs / Symptoms (17)

Feet
Pes cavus  Show images    https://www.datagenno.com/utils/files/images/1327/normalhttps://www.datagenno.com/utils/files/images/1177/normal

Joints and Tendons
Joint contractures

Limbs Abnormality
Widened metacarpal shaft

Metabolic Abnormality
Elevated IL1-beta
Elevated IL6
Elevated antinuclear antibody (ANA) (speckled pattern)

Performance
Abnormal gait

Skeletal
Carpal osteolysis
Fusiform finger swelling
Interphalangeal joint erosions
Osteoporosis
Pes planus  Show images    https://www.datagenno.com/utils/files/images/871/normalhttps://www.datagenno.com/utils/files/images/1179/normalhttps://www.datagenno.com/utils/files/images/870/normal
Tarsal osteolysis
Thin metacarpal cortices
Thin metatarsal cortices

Skin
Hyperpigmented erythematous lesions
Subcutaneous nodules (interphalangeal joints, knees, feet, elbows, pretibial)