MUCOPOLYSACCHARIDOSIS

MUCOPOLYSACCHARIDOSIS TYPE I
MUCOPOLYSACCHARIDOSIS TYPE II
MUCOPOLYSACCHARIDOSIS TYPE III
MUCOPOLYSACCHARIDOSIS TYPE IV
MUCOPOLYSACCHARIDOSIS TYPE VI
MUCOPOLYSACCHARIDOSIS TYPE VII
MUCOPOLYSACCHARIDOSIS TYPE IX
Abdomen
Umbilical hernia
Cardiovascular
Cardiac failure
Cardiomyopathy
Murmurs
Valvular abnormalities
Craniofacial
Arachnoid cyst
Chronic rhinorrhea
Coarse facies with full lips
Escafocefalia with frontal prominence
Flared nostrils
Frontal prominence
Hazy corneas
Inner epicanthal folds
J-shaped sella turcica
Low nasal bridge
Macrocephaly
Micrognathia
Mucoid rhinitis
Prognathism
Scaphocephaly
Thick lips
Gastrointestinal
Hepatomegaly
Hepatosplenomegaly
General
Carpal tunnel
Edema-like swelling of optic disk and macula
Impairment of growth
Progressive juxta-articular cystic lesions in hands and feet
Sleep apnea
Tracheal stenosis
Trigger thumb
Genitourinary
Hydrocele
Inguinal hernia
Proportionately more dermatan sulfate than usual
Growth
Deceleration of growth
Growth deficiency
Short trunk
Hands
Claw-hand deformities
Hearing
Deafness
Middle ear fluid
Limbs Abnormality
Carpal tunnel syndrome
Femoral head dysplasia
Large and short hands and feet
Small carpal bones
Mammary
Tuberous breast deformity
Metabolic Abnormality
Excretion of Dermatan Sulfate
Excretion of Herparan Sulfate
Neurologic Abnormality
Communicating hydrocephalus
Mental deterioration
Psychosis
Ocular
Corneal opacification
Glaucoma
Myopathy
Myopia
Ocular hypertelorism
Open-angle glaucoma
Retinal dysfunction
Retinal pigmentation
Oral
Broad mouth
Dental abnormalities
Enlarged tongue
Hypertrophied alveolar ridge and gums
Hypoplasia of mandibular condyles
Macroglossia
Prominent lips
Performance
Grossly retarded progress ( at 6 to 12 months )
Little if any impairment of intelligence
Mental deficiency of mild to moderate
Renal
Nephrotic syndrome
Skeletal
Anterior vertebral wedging
Broadening of bones
Diaphyseal broadening of short misshapen bones
Dysostosis multiplex
Flaring of the rib cage
Joint limitation
Kyphosis gibbus
More limitation of extension than flexion
Odontoid hypoplasia
Short neck
Thoracolumbar gibbus
Widening of medial end of clavicle
Skin
Hirsutism
Thorax
Pectus carinatum