Signs / Symptoms (9)
| General |
|---|
| Ragged-red muscle fibers |
| Hearing |
|---|
| Sensorineural hearing loss |
| Metabolic Abnormality |
|---|
| Defect in translation of all mtDNA-encoded genes |
| Serum pyruvate or pyruvate and lactate elevated |
| Muscle |
|---|
| Muscle weakness |
| Neurologic Abnormality |
|---|
| Ataxia |
| Myoclonus epilepsy |
| Spasticity |
| Ocular |
|---|
| Myopathy |