Signs / Symptoms (9)
General |
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Ragged-red muscle fibers |
Hearing |
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Sensorineural hearing loss |
Metabolic Abnormality |
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Defect in translation of all mtDNA-encoded genes |
Serum pyruvate or pyruvate and lactate elevated |
Muscle |
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Muscle weakness |
Neurologic Abnormality |
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Ataxia |
Myoclonus epilepsy |
Spasticity |
Ocular |
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Myopathy |