SPINOCEREBELLAR ATAXIA XXIII

Subtype of SPINOCEREBELLAR ATAXIA

Craniofacial
Ocular dysmetria
General
Onset after age 40 years 
Slow progression 
Neurologic Abnormality
Cerebellar atrophy
Cortical and subcortical atrophy
Decreased vibratory sense in the lower limbs 
Demyelination of the posterior and lateral columns of the spinal cord
Dysarthria
Extensor plantar responses
Gait ataxia 
Limb ataxia
Mixed axonal polyneuropathy
Neuronal loss in the Purkinje cell layer of the cerebellar vermis
Neuronal loss in the dentate nuclei
Neuronal loss in the inferior olives
Thinning of the cerebellopontine tracts
Tremor
Ocular
Slow saccades
Performance
Hyperreflexia
Mental retardation